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1 Departments of Periodontology and Oral Biology and the Periodontal Disease Clinical Research Center, State University of New York at Buffalo, Buffalo, New York 14214
Joseph J. Zambon, D.D.S., Ph.D., 222 Foster Hall, State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214
The present report reviews data implicating Actinobacillus actinomycetemcomitans in the etiology of human periodontal disease. Recent data are also presented relative to: (1) serological studies of this micro-organism using monoclonal antibodies and the serodiagnosis of A. actinomycetemcomitans infections; (2) chsracterization of the serotype antigens; (3) studies of the serotype distribution of A. actinomycetemcomitans in extraoral infections; and (4) examination of the correlation between A. actinomycetemcomitans colony morphology and fimbriae.
Note:
We wish to thank Dr. R.E. Weaver of the Centers for Disease Control for his assistance in supplying many of the extra-oral strains of Actinobacillus actinomycetemcomitans.
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